Posted by kingcolon on December 8, 2007, at 1:17:44
In reply to Cymbalta, Remeron, and Wellbutrin, Oh My!, posted by BGB on December 5, 2007, at 18:12:30
Here's an abstract that shows promise for Provigil for bipolar depression.
Modafinil Shows Promise for Bipolar Depression
A study involving 85 patients with bipolar disorder suggests that modafinil (Provigil), a drug indicated for sleep disorders, effectively controls the depressive symptoms associated with bipolar disorder.
"There are very few treatments for the depressive phase of bipolar disorder, and as a result there is an urgent need to evaluate potential new therapeutics," said Mark Frye, MD, director of the Mayo Clinic Mood Disorders Clinic and Research Program, Rochester, Minn.
After 6 weeks, 44% of the patients in the modafinil group reported symptom improvement, and 39% said that their symptoms were in remission, compared with 23% and 18%, respectively, for the placebo group.
Modafinil is often called the "wake-up pill," because it is indicated to treat patients who suffer from excessive sleepiness associated with narcolepsy, obstructive sleep apnea, and shift-work sleep disorder.
Source:
Belmaker RH. Modafinil add-on in the treatment of bipolar depression. Am J Psychiatry. 2007;164:1143-1145.
poster:kingcolon
thread:798987
URL: http://www.dr-bob.org/babble/20071204/msgs/799464.html