Posted by Quintal on August 22, 2007, at 10:56:26
In reply to moclobemide,Phenelzine(Nardil) comparision?, posted by jhj on August 22, 2007, at 3:55:03
I took moclobemide for six months at the maximum dose back in 2003. It was utterly useless for me. The only effect I noticed was insomnia and a bit of agitation at the beginning. I haven't read of a single long-term success story with this drug, though there may well be one somewhere.
Dr. Ken Gillman is a (now retired) psychopharmacologist and psychiatrist, and he used the older non-selective, irreversible MAOIs to treat patients for most of his career; becasue he found them to be the most reliably effective antidepressants. This is his opinion of moclobemide:
____________________________________________________Many clinicians are finding that the new MAOI (or 'RIMA'), moclobemide, is not an effective antidepressant; this view is substantiated by some clinical trials which constitute evidence that moclobemide is no more effective than placebo. In my opinion it is totally ineffective, I gave up using it years, no decades, ago. The minimal effect it has on neurotransmitters is detailed in my recent review.
http://www.psychotropical.com/maois_full.shtml
__________________________________________________I'd recommend reading the full website. There are plenty of references to studies that you could offer your psychiatrist in support of trying phenelzine before moclobemide. If your psychiatrist is one of the paternalistic types that demands obedience to his commands, and puts that above your wellness, then I suppose you will just have to give moclobemide a shot. There are always exceptions and it may work for you of course.
Q
poster:Quintal
thread:777738
URL: http://www.dr-bob.org/babble/20070815/msgs/777774.html