Posted by linkadge on June 28, 2007, at 9:39:17
In reply to Re: amantadine also linked to cardiac valve damamge » linkadge, posted by saturn on June 27, 2007, at 21:32:24
What scares me the most is this: The possable connection between these drugs and this sort of problem is not so easy to spot if you aren't looking.
It is not going to jump out at you.
When the initial suspicion that the two agonists were causing problems arose, researchers had grosly underestimated the occurance of the problem.
Apparently more than a quarter of people who had taken one of the recalled agonists suffered significiant cardiac valve dammage. Their estimates were far fewer than these.
Unless a person has an echocardiogram, there is no way to detect such valve damage untill the symptoms are so severe that the valves likely need to be replaced.
Certain migrane medications are also on the list, as well as ecstacy. But SSRI's are 5-ht2b agonists plain and simple.
The reason the fenfluramine problem was detected so quickly, was that it was being used in overwieght individuals who are going to naturally have more heart problems requiring cardiac imaging.
Anyhow, I wouldn't be suprised if we see a lot more drugs being pulled in the near future.
Well, I can't say I didn't try to warn people.
Linkadge
poster:linkadge
thread:766225
URL: http://www.dr-bob.org/babble/20070622/msgs/766400.html