Posted by jealibeanz on March 9, 2007, at 5:03:53
In reply to Re: GSK and Fabre-Kramer make agreement on Gepirone ER, posted by linkadge on February 10, 2007, at 20:17:04
> Yeah, I pray they are not toying with us again. This is a treatment option that we deparately need.
>
> A cleaner, more slective buspar could offer many people with either an effective monotherapy for anxiety/depression or a useful adjunctive in depression, schizophrenia, and even parkionsons, or cognative disorders.
>
> Linkadge
OK, finally someone who is acknowledging this is somewhat like Buspar! I thought so, but couldn't fully understand the mechanisms.Buspar does state that hits all sorts of receptors-- 5-HTP, dopamine, alpha, histamine. So this is the selective version.
Hmm... I don't know what to think about this.
I took Buspar very briefly, after taking Paxil, my first AD for about a month for anxiety. I quit Paxil because of major weight gain, so my doc switched me. The weight gain continued.
I don't remember feeling any therapeutic effects of either Paxil or Buspar, I think because I was not on them long enough and because I was a teen with a whole lot going on. The anxiety was gonna be there with or without meds, and it's clouded my memory and self-reflection of the time period.
I switched to Wellbutrin right after that. Again I don't remember therapeutic benefits. Actually I remember being pretty anxious and depressed, but afraid of stopping in case it was helping a little. I did quit after 4 months though, because I gained 20 lbs on Wellbutrin (who knows why... some say this does target serotonin receptors a little, possibly due to the other things that the reuptake inhibitors hit in the brain or the rest of the body), while working out twice a day, ha ya, go figure. I remember feeling like I was being lifted out of a fog (aka apathy).
My next agent was Klonopin and Adderall. I didn't take it longer than a few days... parental disapproval... I was then scripted it 2 years later. Klonopin made me feel drug. Adderall made me crash into a depression... enter: the Effexor experience...
Effexor made me feel really good for about a week. Then it made me so unemotional I had to remind myself to react appropriately to the outside world, otherwise I was content to stare at walls. That was the decided point of me quitting. I decided I would rather feel unhappy than feel nothing at all. Oh yeah, and it made me so nausous I couldn't eat, yet gained 20 lbs in the 7 weeks I was on it.
Haha... so, to make a long story short, I don't think I will enjoy anything that targets serotonin. My body seems to dislike it. My doctor and PA always seem a little surprised at my extreme reactions to these antidepressents and anti-anxiety meds.
I'm not the norm. Leaves me with little options for depression unless I want to try another and be fat and apathetic. For anxiety at least I can have Xanax.
poster:jealibeanz
thread:731652
URL: http://www.dr-bob.org/babble/20070308/msgs/739481.html