Posted by yxibow on March 8, 2007, at 2:12:12
In reply to Re: Differences between alprazolam and clonazepam, posted by Squiggles on March 7, 2007, at 20:52:35
> > Hello, I tried 0.25 mg alprazolam or clonazepam at night on different days and the effect I noticed was different.
> >
> > Alprazolam seems to have a more clear anxiolytic effect with more deshinibition during the next day (I do more things), it improves my mood, which clonazepam seems not to do.
> >
> > Anyone noticed this?.
>
> Yes, it may be because clonazepam is about 10 or 20 times more potent than alprazolam.
No, clonazepam is only about 5 times more potent (Dr. Bob's first chart is fairly accurate from my experience with 4 benzodiazepines), but it is more subtle, and has a slower term of uptake.Alprazolam, Xanax, has a mild antidepressant effect for the short term use of it because of the euphoria that is obtained from the immediacy of the uptake of the agent.
Its why I still say often that it should only be used PRN (pro re ne), as needed, because that "immediacy" (gotta get rid of this anxiety) will eventually start to fade a bit and if habituation occurs, one will have to dial way back to get any of that sharp crisp feeling again.
-- tidings
poster:yxibow
thread:739042
URL: http://www.dr-bob.org/babble/20070302/msgs/739134.html