Posted by Quintal on December 22, 2006, at 18:41:23
In reply to Re: Social Anxiety in the EXTREME!!! Advice Request. » NYCguy, posted by blueberry1 on December 22, 2006, at 17:46:18
>Solian was tested against paxil for anxiety and depression. Both were similar in response, except that solian had the added bonus of significantly boosting psychosocial functioning, which paxil didn't. Amisulpride low dose is known for its antidepressant, antianxiety, and pro-motivation pro-interest pro-pleasure qualities. The first week or so it can have some anxiety, insomnia, agitation type side effects. After that it is very tame. The only lingering side effect really is sexual dysfunction requiring viagra for males. I tried it 10 years ago, am expecting an order to arrive soon, and it was an amazing medication for feeling perfectly comfortable in a crowd. It goes well with benzos. It is an antipsychotic at high doses (300mg - 800mg), but an antidepressant at low doses (25mg - 100mg). Since it stimulates dopamine at low doses, it does not make sense to me how it can work for social anxiety, but it just does. It is very clean affecting on 2 specific receptors in very specific parts of the brain.
>I would second Solian. It worked very well for me when I happened to stumble across an old packet a few months ago. I was able to walk down the street in the middle of the day without any anxiety for the first time in years. I grew wary of recommending it here though because I tended to get objections from people who suffered serious sexual dysfunction from it long term, blueberry1 included ;-)
I've never taken it longer than two months but I don't recall sexual dysfunction being a problem for me in that time. The sexual dysfunction seems to be caused by elevated prolactin levels and I believe we were looking into ways of lowering/preventing it. I think someone posted that pre-treatment with Depakote could suppress amisulpride induced prolactin elevation. Someone else had used bromocriptine for this purpose but I don't recall the outcome.
Q
poster:Quintal
thread:715719
URL: http://www.dr-bob.org/babble/20061217/msgs/715764.html