Posted by SLS on October 6, 2006, at 17:31:48
In reply to Re: Imipramine vs. Desipramine for Melancholic Dep » sregan, posted by Squiggles on October 6, 2006, at 15:46:56
> Desipramine is weaker; imipramine is the
> strongest for major depression;I agree.
Of the tricyclics, though, clomipramine (Anafranil) has it beat.
Both drugs can leave one feeling a little stupid. The anticholinergic properties produce some cognitive impairments in some people. I feel a cognitive dulling with imipramine, but it is tolerable. Of course, there is some speculation that the anticholinergic effects of these drugs might be contributing to their antidepressant effects.
- Scott
poster:SLS
thread:692126
URL: http://www.dr-bob.org/babble/20061003/msgs/692477.html