Posted by cache-monkey on January 16, 2006, at 21:07:28
In reply to Re: benzodiazepines prolactin levels » cache-monkey, posted by zeugma on January 13, 2006, at 17:12:57
Ah, I understand that effect with the APs. But it struck me as interesting that the poster had elevated prolactin on selegiline... From what I've read the MAO-B inhibition should lead to increased dopamine concentrations, more D-2 stimulation, and if anything lower prolactin...
~cache-monkey
> the reason antipsychotics have hyperprolactinema as a fairly frequent side effect is due to dopamine blockade.
>
> DA agonists such as bromocriptine are prescribed as treatment when this condition occurs spontaneously, i.e. not med induced. I suppose bromocriptine would simply negate the effect of the AP, were it prescribed concurrently.
>
> Benzodiazepines in general appear to lower prolactin levels, with the interesting exception of alprazolam. Check Pub Med.
>
> -z
poster:cache-monkey
thread:597892
URL: http://www.dr-bob.org/babble/20060115/msgs/599813.html