Posted by SLS on October 25, 2005, at 18:03:56
In reply to Re: Use of opiates in treating depression, posted by Chairman_MAO on October 25, 2005, at 17:41:28
Hi.
> If your doctor deems "opioid therapy" appropriate, there will be no reason for him to Rx you anything with an NSAID in it; they just add toxicity. There's really no reason for him to start with anything less than OxyContin.
I agree...
> That said, I recommend buprenorphine as the first-line opioid for depression. Far milder withdrawal than full agonists, vastly increased safety in overdose, and a unique receptor binding profile (kappa antagonism, conferring antipsychotic/antimanic activity possibly) make it ideal for depression. Many people prefer buprenorphine to traditional opioids for depression because it tends to be more activating as well.
I agree...
> It's also superb for anxiety; I believe it should be prescribed in lieu of benzodiazepines in many circumstances (hell, its withdrawal syndrome is a lot easier to deal with and never life-threatening!).
I gotta think about this one for awhile. The nice thing about buprenorphine is that it is self-limiting with regard to any possible euphoriant effects.
- Scott
poster:SLS
thread:98310
URL: http://www.dr-bob.org/babble/20051024/msgs/571812.html