Posted by Squiggles on September 1, 2005, at 7:31:54
In reply to Re: Imipramine versus desipramine, posted by SLS on August 16, 2005, at 15:32:51
> I forgot to mention that desipramine is the immediate metabolite of imipramine. If you take imipramine, you will be supporting a therapeutic blood level of desipramine at the same time. If imipramine doesn't work at high dosages, it is unlikely that desipramine will.
>
> If side effects with imipramine are intolerable despite an antidepressant response, but desipramine proves inadequate, you can try either adding some Prozac to the desipramine or switching to nortriptyline.
>
>
> - ScottThank you Scott, and others who have helped
with the imipramine/desipramine question.
From what i read on the net desipramine *is*
weaker at least in side effects, and does
seem to take a larger dose than imipramine to
work. At 200mg it was just weaker than
imipramine at the same dose, and i suggested
to my friend to raise it; and her dr. ok'd
a dose up to 300mg - less side effects, equivalent
antidepressant effect.Thank you.
Yes!Squiggles
poster:Squiggles
thread:542498
URL: http://www.dr-bob.org/babble/20050901/msgs/549605.html