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Re: Allergic to patch? » gromit

Posted by KaraS on June 18, 2005, at 2:33:19

In reply to Re: Allergic to patch? » KaraS, posted by gromit on June 17, 2005, at 23:49:25

> > Would the sublingual selegiline also obviate the need for the MAOI diet? If so, then why do we need to wait for the patch at all? Maybe it's a lot harder to get doctors to prescribe the sublingual selegiline where as if the patch were released and promoted here, then mainstream doctors would be willing to prescribe it.
>
> I've wondered the same thing about sublingual selegiline, I know I've read that SHOULD be the case. I don't think there is a sublingual form available in the US. I imported some liquid, can't remember the measurement they use but I think it amounted to 300 mg, for about $90. Depending on your dose that could be pretty reasonable. At 10 mg a day it isn't, at least for me.
>
> I've searched for, but never found again a post where someone claimed a really low dose, like 1-2 mg a day, would eventually give almost complete inhibition.
>
>
> Rick
>

Actually it may be a moot point. I found the following on PubMed. It's not encouraging.

Sublingual selegiline: new formulation. New formulation: new risk of oral adverse effects.

[No authors listed]

There is no evidence that sublingual selegiline reduces the risk of adverse effects associated with oral selegiline. On the contrary, it has a potential for oral ulceration and stomatitis

PMID: 14619897 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14619897&dopt=Abstract


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poster:KaraS thread:513663
URL: http://www.dr-bob.org/babble/20050617/msgs/514793.html