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Re: Prochlorperazine potency

Posted by yxibow on May 18, 2005, at 18:04:59

In reply to Re: Prochlorperazine potency » xbunny, posted by ed_uk on May 18, 2005, at 13:02:48

> I think your mum should get a different antiemetic! There are many options.
>
> Kind regards,
> Ed.

I would agree.. depending on where she lives, there are much newer drugs, the 5HT3 antagonists, ondansetron (Zofran), the first, and the newer ones granisetron (Kytril) and dolasetron (Anzemet), which are used in chemotherapy and postoperative nausea and also in conjunction with HIV drug therapy among others. They are more expensive than the phenothiazine or related neuroleptic antiemetics but they dont carry the risk of EPS and especially tardive dyskinesia which in the risk category of older women is much greater -- not to scare you about your mother.

I would think if your insurance can pay for one of them (Zofran is probably cheaper than the newer ones) its a much better option, unless your doctor has some particular reason to think of drug-drug interactions. Some of these newer drugs are also available in injectible form if your doctor thinks that your mother cannot swallow them.

Hope she feels better.
Tidings

 

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poster:yxibow thread:499422
URL: http://www.dr-bob.org/babble/20050516/msgs/499546.html