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Re: Questions on NE alpha antagonists » ravenstorm

Posted by Ritch on February 8, 2005, at 0:19:49

In reply to Questions on NE alpha antagonists, posted by ravenstorm on February 7, 2005, at 20:43:18

>..First, what is the difference between an
NE-alpha1 antagonist and an NE-alpha2 antagonist?

Second, if I am irritable, angry and anxious on remeron, which works as an NE-alpha2 antagonist, would I also, in theory, find buspar (which also works as an NE-alpha2 antagonist) to cause the same side effects?

What about drugs that are NE-alpha1 antagonists? Serzone falls into this category, and I was never angry or anxious on serzone


I found Buspar to defnitely trigger very very bad temper spells for me, very similar to Remeron. The alpha-1 antagonists that I've taken such as trazodone and serzone, and Mellaril.. etc. didn't make me angry either. What those seem to do is cause *dizziness* as a s/e more than anything else, and nasal congestion (vasodilation?). I would like to see a good explanation of the differences too..


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