Re: BuSpar = increased anxiety? (alpha-2 antag.?)

Posted by linkadge on December 20, 2004, at 20:05:13

In reply to Re: BuSpar = increased anxiety? (alpha-2 antag.?) » olysi79, posted by cache-monkey on December 20, 2004, at 18:29:32

Buspar acts as a bit of an antagonist at the dopamine d2 receptors. But on the other hand it will increase DA in the frontal cortex via activation of the 5-ht1a receptors.
The alpha-2 autoreceptors act as an inhibitory thermostat on NE release. Ie when the receptors get activated, they turn down the firing rate of norepinephrine.

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BuSpar = increased anxiety? (alpha-2 antag.?) cache-monkey 12/20/04
Re: BuSpar = increased anxiety? (alpha-2 antag.?) linkadge 12/20/04
Re: BuSpar = increased anxiety? (alpha-2 antag.?) olysi79 12/20/04
Re: BuSpar = increased anxiety? (alpha-2 antag.?) » linkadge cache-monkey 12/20/04
Re: BuSpar = increased anxiety? (alpha-2 antag.?) » olysi79 cache-monkey 12/20/04
Re: BuSpar = increased anxiety? (alpha-2 antag.?) linkadge 12/20/04
Re: BuSpar = increased anxiety? (alpha-2 antag.?) PeterJ 12/21/04
Re: BuSpar = increased anxiety? (alpha-2 antag.?) » PeterJ ed_uk 12/22/04
Buspirone + Clonidine ed_uk 12/22/04
Re: BuSpar = increased anxiety? (alpha-2 antag.?) PeterJ 12/22/04

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