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Sibutramine (Meridia / Reductil) and depression

Posted by ed_uk on December 20, 2004, at 18:27:12

Hi,

Sibutramine (Meridia / Reductil) is a serotonin and norepinephrine reuptake inhibitor, it also inhibits dopamine reuptake to a lesser extent. It is used as a treatment for obesity. Suprisingly, the development of sibutramine as an antidepressant was discontinued due to apparant lack of efficacy in clinical trials.

Has anyone ever found sibutramine to be a useful treatment for depression?

Ed.

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poster:ed_uk thread:432171
URL: http://www.dr-bob.org/babble/20041217/msgs/432171.html