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Re: wuss central and aspartane » rainy

Posted by Larry Hoover on November 9, 2004, at 14:38:50

In reply to wuss central and aspartane, posted by rainy on November 9, 2004, at 14:12:02

> Ralph Walton (my ex pdoc, btw, before we moved) has published some studies that you can read on medline, I think, that indicate aspartane makes depression worse.
> Just a heads up. He didn't ask me so I didn't tell him that I was drinking pints of it every day. Maybe the ADs would have worked better had I known.
> Thanks again for your support.
> relieved rainy

I think Walton would have wanted to know that. Just a guess.

For those interested in seeing the type of symptoms reported in aspartame-sensitive depressives, see the full text link. The abstract is below that.

Lar

http://www.mindfully.org/Health/Aspartame-Adverse-Reactions-1993.htm

Biol Psychiatry. 1993 Jul 1-15;34(1-2):13-7.

Adverse reactions to aspartame: double-blind challenge in patients from a vulnerable population.

Walton RG, Hudak R, Green-Waite RJ.

Department of Psychiatry, Northeastern Ohio Universities College of Medicine, Youngstown.

This study was designed to ascertain whether individuals with mood disorders are particularly vulnerable to adverse effects of aspartame. Although the protocol required the recruitment of 40 patients with unipolar depression and a similar number of individuals without a psychiatric history, the project was halted by the Institutional Review Board after a total of 13 individuals had completed the study because of the severity of reactions within the group of patients with a history of depression. In a crossover design, subjects received aspartame 30 mg/kg/day or placebo for 7 days. Despite the small n, there was a significant difference between aspartame and placebo in number and severity of symptoms for patients with a history of depression, whereas for individuals without such a history there was not. We conclude that individuals with mood disorders are particularly sensitive to this artificial sweetener and its use in this population should be discouraged.

 

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