Posted by steve12 on September 16, 2004, at 11:35:36
In reply to Re: Cymbalta honeymoon is over » Mistermindmasta, posted by alesta on September 15, 2004, at 23:16:34
I think 5HT is involved in anxiety -- certainly for most people, paxil, prozac, etc relieve anxiety. I would agree that dopamine stimulation is underused in depression -- but for a different reason. Thers is emerging evidence that chronic administration of SSRI's may downregulate DA receptors, which may account for the cognitive fuzzieness that many depressives report. Often, doc's will augment SSRI's with Wellbutrin for this -- but Wellbutrin really acts on NE not DA. Really, only stimuants will do the trick.
I think that NE (and cymbalta's re-uptake of it) is repsonsible for the anxiety that many experience. But that's just my 2 cents :)
poster:steve12
thread:390747
URL: http://www.dr-bob.org/babble/20040915/msgs/391495.html