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Re: What side effects from too much PARNATE? » SLS

Posted by don_bristol on August 10, 2004, at 16:55:51

In reply to Re: What side effects from too much PARNATE?, posted by SLS on August 8, 2004, at 12:30:30

>> What side effects would I get which told me
>> that my dose of Parnate was getting too high for me?
>>
>> Apart from increased sleeplessness what side effects
>> are there which stop one from going higher on Parnate?
>>
>> Is it (postural) hypotension?
>> Is it headaches?


Scott wrote:
>
> Postural hypotension is a pretty reliable indicator of
> dosage. One of my doctors considered a 10% drop in blood
> pressure upon rising from a chair to be expected once you
> reach a therapeutic level.

Hi Scott, it's Don here. It sounds to me like it might be tricky to work out a 10% drop. My blood pressure meachine varies quite enough between repeated readings (maybe 5%).

ISTR that a symptom of postural hypotension is seeing stars (and if it is really bad then there is fainting). But I don't think that would happen with just a 10% drop in BP.

> It's pretty hard to take too much Parnate. You can titrated
> it up to dosages in excess of 60mg if you tolerate the
> side effects.

I guess the food (in)tolerance gets worse as you reach those high levels of Parnate. maybe that is one reason to go easy?

> Some possible indicators of taking a higher dosage than
> is optimal might be hyperreflexia and myoclonic jerks.
> I'd like to see what other people have to say about this.


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