Posted by karen m. on August 9, 2004, at 0:38:44
In reply to Re: Lamictal dosage question?, posted by SLS on August 8, 2004, at 14:41:54
> > So are you saying 200mg is the minimum dose to see if Lamictal can be used for monotherapy for depression?
> >
> > Seems like I've seen several threads where after 150-200mg you get increased mood stabilization but not much more antidepressant effects.
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> I don't recieve the maximum antidepressant benefit from Lamictal until I reach 300mg. However, I think my case is too atypical to use as an example. Lamictal is sort of funny. A lot of people experience a wonderful antidepressant effect during the first few weeks at dosages of 50-75mg. This more often than not dissipates quickly, and higher dosages are necessary to recapture any improvement. I don't see that many people having success with Lamictal monotherapy for depression. It seems to be more effective as an augmentor. However, I just don't think there is enough uniformity in the way people respond to Lamictal to be able to designate absolute dosage thresholds for therapeutic effect. 200mg has been the most common average dosage I have seen quoted for use in bipolar depression.
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> - Scotti agree with scott in terms of i didn't get much out of lamictal until i reached 300 mg. it kind of kicked in then. my pcdoc is determined to use lamictal as a monotherapy. as scott mentioned, there seem to be periods of more effectiveness than others. i have not gone back into a depression since starting lamictal but on the flip side i am still irritable, anxious and uncoordinated in brain and body movements after finally reaching 300mg. apparently one has to take the good with the bad. i imagine my pcdoc will now increase my dosage since the idea of me grawing my husbands arm off holds little appeal to either of us. i'd be curious to know how those folks that are on a higher dose are doing.
/karen/
poster:karen m.
thread:375339
URL: http://www.dr-bob.org/babble/20040805/msgs/375501.html