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Re: chemical difference between paxil and lexapro » shadowmon

Posted by pellmell on July 4, 2004, at 12:41:15

In reply to chemical difference between paxil and lexapro, posted by shadowmon on July 4, 2004, at 4:23:42

> Does anyone know the difference between what paxil afects and what lexapr affects? Is there any difference?

Check out Dr. Sheldon Preskorn's old columns here:
http://www.preskorn.com/column2.html

They shed a whole lot of light on the differences between the SSRIs. The info on citalopram is applicable to Lexapro, since citalopram and escitalopram are essentially the same drug (escitalopram is citalopram without the inactive enantiomer).

For some reason -- perhaps related in vitro pharmacology, perhaps not -- I respond best to SSRIs that hit the dopamine or norepinephrine reuptake pumps in the test tube, e.g. Prozac (fluoxetine) and Zoloft (sertraline). Though for whatever reasons Effexor just raised my blood pressure slightly and made me really foggy-headed.

My depressive symptoms are mainly cognitive, and involve lots of social withdrawal and the like.

Hope this is of some help to you..

-pm


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