Posted by King Vultan on April 21, 2004, at 8:05:49
In reply to will nardil make my heart race, posted by linkadge on April 20, 2004, at 15:03:53
> will nardil make my heart race like effexor ??
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> I had heart palps galore on Effexor. It is clear to me that I need some noreinephrine action because I still get very panicky on SSRI's. Effexor worked but made my heart race a mile a minaute, this is also why I needed to drop parnate cause the higher doses shot my BP up.
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> Has anyone taken parnate and the others who might know if nardil is very stimulating. (how much less stimulating than parnate is it)
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> Linkadge
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Drugs that have strong effects on norepinephrine reuptake have a tendency to induce tachycardia in susceptible individuals. I did not experience this on Effexor but certainly did on the tricyclics desipramine and protriptyline (Vivactil), as well as Strattera. My resting heart rate rose to as high as 100-110 on both the Vivactil and Strattera.However, Nardil does not generally do this, even though it does have a powerful effect on norepinephrine. Due to the particular mechanism by which MAOIs work, heart rate and blood pressure very often go down; although, this is less true of Parnate. You can think of Parnate as essentially equivalent to Nardil plus a weak amphetamine, a combination that will prove problematic in some instances as far as causing a blood pressure spike. In fact, this is likely the reason that Parnate is more prone to cause spontaneous hypertensive crises (ones occurring without ingesting any of the prohibited drugs or foods) than is Nardil.
My own experience on Nardil, which I've been on since March 1, and on 75 mg/day for almost three weeks, is that my BP has gone down so much I am going to discontinue my lisinopril BP med after tomorrow. Combined with a resting heart rate that is now very often in the mid 50's (normal for me is mid 70's), I am coming close to fainting on occasion from low blood pressure.
Todd
poster:King Vultan
thread:338005
URL: http://www.dr-bob.org/babble/20040417/msgs/338339.html