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Re: Modafinil is a controlled substance !!!

Posted by Clayton on March 18, 2004, at 17:06:27

In reply to Re: Modafinil is a controlled substance !!! » Lycaste, posted by Rick on January 1, 2001, at 22:58:28

Just a brief response. If there really is such a thing a an "acctive perponality", I have it. I was addicted to meth tabs in the 1970s and more recently to Ritilin (a kinder, gentler form of speed). Both quickly build a tolerance and I incessantly bumped the dose to insane levels.

I now use Provigil. It dies NOT give me the euphoric feeling of the CNS stimulants and I do NOT increase the dose I take. I do NOT crave it it. It seems to me to be a marellousous and fairly innocuous drug.

I do not question the studies that demonstartae Provilil's abuse potential. From my personal experience, however, I would have to say that the abuse potention is at least several orders of magnitute lower than the CNS stimulants mentioned above. Personallly, I can't see how , if it doesn't seduce me, it would "hook" anyone.

Provigil has been a marvelous and efficacious adjunct to my depresrion meds (Paxil and Remaron). It also aids my short term memory and helps me to stay focused and on trank at work.

Again, I don't question the research studies, but believe this is a MUCH, MUCH safer alterative to other conventional CNS stimulants.
________________________________________________
Good point. I recalled seeing an abstract about that study, too. I easily dug it up again by entering "modafinil and rats and self" in the Medline search box. Based on the reinforcing behavior seen in rats, the authors of that 1996 study concluded that high doses of modafinil might cause addiction.

Here is what I found on Medscape's current modafinil monograph:

Abuse and Misuse Potential:

Patients should be followed closely during modafinil use for possible signs of misuse or abuse (e.g., incrementation of doses, drug-seeking behavior), especially those with a history of drug or stimulant abuse (e.g., amphetamine, cocaine, methylphenidate). Although modafinil can produce psychoactive and euphoric effects and feelings consistent with other CNS stimulants (e.g., methylphenidate), current evidence indicates that the risk of abuse or misuse of modafinil is lower than that associated with such CNS stimulants that are subject to control as schedule II drugs (e.g., amphetamine, methylphenidate). Therefore, modafinil is only subject to control as a schedule IV drug.

Rick


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poster:Clayton thread:50297
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