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Re: neuroleptic weight gain and response.

Posted by jtevers on December 10, 2003, at 16:41:55

In reply to Lamictal weight gain? » jtevers, posted by katia on December 10, 2003, at 0:05:04


> I'm currently on Lamictal at 175mg. I also take 600-900mg of Neurontin and 7mg of Seroquel both for sleep. I seem to be gaining weight. I wonder if it's this Neuron. and Seroquel mix like you or the Lamictal. How much are you on?
> thanks.
> katia

katia, it's funny to see the parallels our treatment has taken... both having been prescribed seroquel and neurontin and currently struggling with weight gain.

i wonder if perhaps you are confused about one of your meds... i have never heard of anybody taking only 7 mgs. of seroquel ... i take 600 mgs in divided doses throughout the day, it makes me terribly sleepy so i take a majority at nite.

i take 1800 mgs of neurontin in three divided doses of 600 each throughout the day and while taking neurontin has become to feel really benign, i still question whether it , or the seroquel, is the root of my weight gain.

i seem to have gained an additional amount when my dose of neurontin was increased last winter. since many professionals have told me that weight gain by neurontin is dose-related... i continue to research alternatives to, not only my antipsychotic (seroquel), which is almost definitely a contributing factor to the weight gain, but also to my mood stabilizer (neurontin).
very soon i will attempt to exchange gabatril for neurontin and abilify for seroquel ... both of which have less propensity to cause weight gain and may additionally normalize my sleep ( i sleep nearly 10 hours on seroquel treatment ).

i, too, am currently on a trial of topamax. i have just started, though, and am only on 25 mg. at nite this week... it is my understanding that the mechanism of weight loss induced by topamax is more complicated than simply appetite reduction and has been studied for some time as a counterbalance to the weight gain caused by antipsychotic treatment ... weight gain that often, otherwise, does not respond to diet or exercise?

i will start slowly, on the topamax, and am well versed in all the gnarly side effects i will probably encounter and hope to reach 200 mgs. in 2-3 months ... i hope, along with stupification, to see some weight loss.

katia, et. al.
sorry i can't tell you which of your meds is responsible for the weight gain... we seem to have the same questions and share similar odds in our treatment.

ironically, i know that my future will also see some experimentation with lamictal as, currently, my neurontin seems to work well at quelling manic bouts, but has historically done very little for depressive bouts i experience nearly monthly ... my doctor says the lamictal has both mood-stabilizing and mood-enhancing (antidepressive) qualities ... i'd appreciate knowing your experience with it . the lamictal, by the way, is almost certainly not responsible for the weight gain you've seen ... very rarely is this a side effect to lamictal treatment.


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poster:jtevers thread:5053
URL: http://www.dr-bob.org/babble/20031208/msgs/288512.html