Posted by Peter on October 7, 2003, at 7:10:32
In reply to re: Checking in ... » Peter , posted by lil' jimi on October 6, 2003, at 22:22:12
> hi Peter,
>
> i'm thinking that we have a confusion here that we should clear up for you ...
>
> you write:
> > He said that if my mood is not recognizably improved, we would take the next step of increasing the lex dose. However, I'm concerned about doing this. The lexapro prescribing info that describes the outcomes of the various placebo-controlled trials state that those groups who took 20mg lexapro experienced DOUBLE the SE's than the placebo and 10mg lex groups; it also states that there was no real evidence that the 20mg group experienced more therapeutic effects than did the 10mg group. But, on the other hand, I've heard from many posters that they increased from 10mg and experienced a profound increase in therapeutic effects. But if the stats are correct, do I really want to, by increasing the dose, risk double the side-effects (the ones I just recently got over were bad enough in and of themselves) with a chance of not experiencing any increase in therapeutic effects? I'm confused as to what to do. >
>
> ... now i respect that you do have several irons in the fire about your options here ...
> ... i am addressing only one of your considerations ...
> ... but i feel this is a case of comparing apples to oranges ...
>
> the study's statistics comparing 10 mg's to 20 mg's side-effects have to be comparing groups who start out at 10mg versus 20mg respectively ...
>
> i see this as too far a reach to be compared to a single user going from 10mg to 20mg ...
> ... because this amounts to comparing the SEs of someone going from zero to 20mg ...
> ... to the SEs of someone going from 10mg to 20mg ...
> >>AGH! I completely misinterpreted that info! You're right. Thank you so much for clearing that up for me. I'm much less skeptical and confused about increasing the dose now. Funny, but today I woke up actually feeling ok! For weeks I've been waking up every day feeling exhausted and heavy and moody, like I don't want to face the day. But today was different - my mood seems a bit improved. Cool! Maybe lex is finally working! Maybe increasing the dose will really kick it in more quickly. I'll see what my pdoc thinks I should do. But thanks again for clearing that up, Jim.
>Best,
Peter
poster:Peter
thread:109458
URL: http://www.dr-bob.org/babble/20031004/msgs/266245.html