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Xyrem bibliography (abstracts)

Posted by utopizen on October 3, 2003, at 15:07:41

http://xyrem.com/bibliog.htm

Xyrem
Bibliography

The following bibliography is provided for your information on narcolepsy, cataplexy, and Xyrem (sodium oxybate) oral solution.


1. Anic-Labat, S., Guilleminault, C., et al. Validation of a Cataplexy Questionnaire in 983 Sleep-disorders Patients. Sleep 1999; 22: 77-87

2. Krahn, LE., Black JL., et al. Narcolepsy: New Understanding of Irresistible Sleep. Mayo Clinic Proceedings 2000; 76:185-194.

3. Siegel, JM. Narcolepsy. Scientific American 2000; 1: 76-81.

4. Siegel, JM. Narcolepsy: A Key Role for Hypocretins (Orexins). Cell 1999; 98: 409-412.

5. Douglas, NJ. The Psychosocial Aspects of Narcolepsy. American Academy of Neurology 1998; 50(1): S27-S30.

6. Hublin, C., Partinen, M., et al. Epidemiology of Narcolepsy. Sleep 1994; 17:S7-S12.

7. US Xyrem Multicenter Study Group. A 12-month, open label, multicenter extension trial with orally-administered sodium oxybate for the treatment of narcolepsy. Sleep 2003; 26(1): 31-35.

8. US Xyrem Multicenter Study Group. A randomized, double blind, placebo-controlled multicenter trial comparing the effects of three doses of orally administered sodium oxybate with placebo for the treatment of narcolepsy. Sleep 2002; 25(1):42-49.

9. Black, J., Ristanovich, R., et al. Dose Response Effects of Sodium Oxybate on Polysomnographic (PSG) Measures in Narcolepsy Patients: Preliminary Findings. Sleep 2001; 24(Suppl 1):563K (Abstract).

10. Montplaisir, J., Ristanovich, R., et al. Effects of Sodium Oxybate on Measures of Daytime Sleepiness in Narcolepsy Patients: Preliminary Evidence of Dose-Related Improvements. Sleep 2001; 24(Suppl 1):564K (Abstract).

11. Scharf, M.B., Lai, A.A, et al. Pharmacokinetics of Gammahydroxybutyrate (GHB) in Narcoleptic Patients. Sleep 1998; 2(5):507-514.

12. Scrima, L., Hartman, P., et. al. Efficacy of Gamma-Hydroxybutyrate versus Placebo in Treating Narcolepsy-Cataplexy: Double-Blind Subjective Measures. Biol Psychiatry 1993; 26:331-343.

13. Mamelak, M., Scharf, M., Woods, M. Treatment of Narcolepsy with g-Hydroxybutyrate. A Review of Clinical and Sleep Laboratory Findings. Sleep 1985; 9(1):285-289.
Safety of Xyrem

14. Hagaman, M. Sodium Oxybate is Safe and Well-tolerated when Used for the Treatment of Narcolepsy. Sleep 2001; 24(Suppl 1):569K (Abstract).

15. Hagaman, M. Chronic Administration of Sodium Oxybate Produces Significant and Long-Term Improvements in Narcolepsy Symptoms. Sleep 2001; 24(Suppl 1):574K (Abstract).

16. Hayduk R., Mitler M. Sodium Oxybate Therapy Improves the Quality of Life of Narcolepsy Patients. Sleep 2001; 24(Suppl 1):571K (Abstract).

17. Daniels, E., King, MA, et al. Health-related Quality of Life in Narcolepsy. Journal of Sleep Research 2001; 10:75-81.

18. Goswami, M. The Influence of Clinical Symptoms on Quality of Life in Patients with Narcolepsy. Neurology 1998; 50(1):S31-S36.

19. Black, J. Narcolepsy: Evaluation and Management. CNS News Special Edition 2001; 12:25-29.

20. Hublin, C. Narcolepsy: Current Drug Treatment Options. CNS Drugs 1996; 5(6):426-436.

21. Milter MM, Aldrich MS, et al. Narcolepsy and Its Treatment With Stimulants. Sleep 1994; 17(4):352-371.

"Articles and abstracts are available through Medical Information and Drug Safety at 1-800-521-5169"


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