Posted by Joe Schmoe on October 2, 2003, at 16:19:59
In reply to Choline idea is BS, posted by linkadge on October 2, 2003, at 15:39:12
> When you are coming off a SSRI the LAST think you want to do is boost dopaminergic transmission. This will make you feel worse.
Actually the idea was to boost cholinergic transmission, the lowering of which is supposedly what causes discontinuation syndrome.
Here is a typcial page discussing this:
http://www.bipolarsurvivor.com/ssri.html
The reference is:
Biological Psychiatry Vol. 54, page 534
Selective Serotonin Reuptake Inhibitor Discontinuation Syndrome Is Associated with a Rostral Anterior Cingulate Choline Metabolite Decrease: A Proton Magnetic Resonance Spectroscopic Imaging Study
Marc J. Kaufman, Michael E. Henry, Blaise deB. Frederick, John Hennen, Rosemond A. Villafuerte, Eve P. Stoddard, Mark E. Schmidt, Bruce M. Cohen, and Perry F. Renshaw
> What will help are folic acid, 5-htp, blueberry extract, exercise, and time
Why would 5-HTP (serotonin) help? That is like climbing back on the merry-go-round. I might as well take more Celexa. How will that help my brain get used to lower levels of serotonin again?
poster:Joe Schmoe
thread:264315
URL: http://www.dr-bob.org/babble/20030928/msgs/264996.html