Protein Kinase C inhibitors

Posted by linkadge on July 25, 2003, at 16:34:01

I have been using my manic energies to search for different antimanic agents.
I has come to my attention that most of the effective mood stabilizers have protein kinase c inhibition abilities.

Here are some of the protein kinase c inhibitors that I have tried and there effects.

Vitamin E - Reportedly blunts excess protein kinase c espression. Definately has an antimanic effect at 2000IU. However it has a dopamine enhancing effect, that made me quite irritable.
But it did completely stop all mind racing.
Fish Oil - Works for mind racing and cycling of emotion. Keeps me in a constant state, but again the dopamine effect makes me irritable and angry.
Quercetin - Wonderful wonderful. I say with all honesty that if you are manic, then 500-1000mg od quercetin will definately calm the core of you down. It suposedly is one of the most potent PKC inhibitors (natural) available.
Selenium - Definately will take you out of a manic high, but it makes me depressed if I take more than 200 mcgs.
After the descovery that Tamoxafan was antimanic I have been interested in this area. I am convinced that PKC really is the final common target of mood stabalizers.

Linkadge

Thread

Protein Kinase C inhibitors linkadge 7/25/03
Very Interesting! What is Kinase C? (nm) » linkadge River1924 7/26/03
Re: Very Interesting! What is Kinase C? linkadge 7/26/03
Re: Very Interesting! What is Kinase C? » linkadge samplemethod 7/26/03
A caution linkadge 7/26/03
Links to research involving PKC and mania Shawn. T. 7/27/03
although epsilon involved in anxiety (nm) linkadge 7/27/03

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