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Re: Tricyclics and cognitive impairment... help! » Caleb462

Posted by Ritch on May 7, 2003, at 10:37:41

In reply to Tricyclics and cognitive impairment... help!, posted by Caleb462 on May 6, 2003, at 2:20:53

> Okay... I may be starting Anafranil soon... but maybe not. I'm worried about the anti-chollinergic effect - not so much the dry mouth or urinary retention, but the effect on memory and cognition. I've always had a pretty great memory... I was disorganzied and lazy in school, but did great on tests because I would memorize everything the night before. And not to brag, but I'm also usually regarded as being witty, intelligent, etc. I don't want to lose these things.
>
> So to those who have used tricyclics, particularly Anafranil, has it effected your cognition at all? If so, did it pass? Thanks to all who asnwer!


I was taking a low-dose of amitriptyline (10mg bid) with lithium back in the '80's and I quit it after a month or two because all of my friends found me very "boring" and "unspontaneous". The sedation was fairly heavy, but it lifted some and I felt more focused and energetic after a couple of weeks, though. Doxepin was really a very heavy sedative that never seemed to get any better, I didn't like that one at all. Nortiptyline I found very tolerable, however. I don't know how Anafranil's sedation stacks up to these-I think Anafranil isn't as sedative as doxepin or amitriptyline-maybe it won't be too bad?


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poster:Ritch thread:224624
URL: http://www.dr-bob.org/babble/20030505/msgs/224849.html