Posted by utopizen on April 8, 2003, at 17:37:35
In reply to Re: Alpha blockers treat post-urination dribbling, posted by utopizen on April 8, 2003, at 16:59:10
From
http://www.mc.uky.edu/pharmacology/instruction/pha824ar/PHA824ar.html.
Actions in Benign Prostatic Hypertrophy1.
Prazosin and related analogs also relax the smooth muscle associated with the bladder neck and prostate.
2.
Tamsulosin has a similar action and is also used to treat BPH. Tamsulosin is an example of a drug that is selective for one of the subtypes of the alpha1-adrenergic receptors. This ligand selectively blocks the alpha1A-receptor. The alpha1A-receptor is involved in regulating the smooth muscle tone associated with the prostate. Therefore, tamsulosin selectively antagonizes the receptor subtype involved in regulating prostate function. Tamsulosin is less likely than the prazosin analogs to cause hypotension
poster:utopizen
thread:217027
URL: http://www.dr-bob.org/babble/20030407/msgs/217505.html