Posted by djmmm on December 3, 2002, at 12:00:58
In reply to Anyone w/ good psychopharm. research knowledge??, posted by bampf on December 3, 2002, at 5:41:08
Bupropion has very little affinity for serotonin, in fact, it isn't a very potent/selective drug at all. I beleive it acts mostly as a dopamine antagonist, whereas the metabolites (it has 3 major metabolites) are considered "potent" inhibitors of norepinephrine reuptake.
As far as it being more potent than d-amphetamine, I haven't heard this, I do know that the SSRI Zoloft is a more potent blocker of dopamine reuptake than wellbutrin...
poster:djmmm
thread:130355
URL: http://www.dr-bob.org/babble/20021203/msgs/130398.html