Posted by pharmrep on November 2, 2002, at 18:24:52
In reply to Re: Anyone switched to Lexapro? « ggrrl, posted by Katarina on November 2, 2002, at 8:24:21
> I understand how the mirror image isomer acts, and the proposed efffect, yet I don't understand what makes one SSRI better than another, and why they would make me feel so strange. Is it like acetominophen vs. ibuprofen for a fever...both reduce it yet each works differently in the body? I've read so much about this stuff, yet am not further enlightened, plus doc gets tired of my armchair doctor-babble.
> Any thoughts, suggestions, etc. are welcome.
> Thanks,
> Kat
>*** You are correct...the 6 SSRI's before Lexapro were very similar. (Prozac,Paxil,Zoloft,Celexa,Luvox,Serzone) All showed similar efficacy in trials against each other...they would just differ in side effect profiles, and Drug-to-drug interactions, and other secondary features...(dosing, etc.) Lexapro is the 1st SSRI to demonstrate greater efficacy, while not having "baggage" to go with it..like side efx. Lexapro works in 1-2 weeks for most people, has side effects comparable to placebo (per the FDA in the package insert), has a 10mg starting and maintenace dose (titrating is minimized), has the best p450 profile (lack of drug-interactions), it is the least expensive as well. There are many reasons to like Lexapro, it has many advantages over other SSRI's. It's new, yet many Dr's are using it already because they are seeing what is mentioned above and how it helps their patients
poster:pharmrep
thread:109458
URL: http://www.dr-bob.org/babble/20021101/msgs/126219.html