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'Failed' lexapro study

Posted by dr. dave on October 29, 2002, at 5:41:16

In reply to Re: Citalopram pharmacology » dr. dave, posted by Malcolm on October 29, 2002, at 2:13:41

I was interested to discover in the product monograph (page 22) on www.cipralex.com that one of the two initial US studies of Lexapro/Cipralex showed no statistically significant difference between escitalopram and placebo, nor citalopram and placebo.

What does this mean? I do think that escitalopram and citalopram are both effective, but that they are virtually identical in practice, and their benefit over placebo is a lot less than you might be led to believe by the rather feverishly optimistic marketing. Optimism about treatment for depression is good, but to treat depression realistically and seriously you need to have an accurate idea of what your tools can achieve.


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poster:dr. dave thread:109458
URL: http://www.dr-bob.org/babble/20021025/msgs/125641.html