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lexapro (P.I.) dose dependant adverse events

Posted by pharmrep on September 1, 2002, at 0:00:38

In reply to Re: Lexapro side-effects » dr dave, posted by pharmrep on August 31, 2002, at 22:13:49

Some of the more common adverse events (as listed in the package insert) are as follows:

adverse event......Placebo.(311 patients)/...10mg Lexapro.(310 patients)/...20mg Lexapro (125 patients)
insomnia..............4%.................................7%..........................................14%
diarrhea..............5%.................................6%..........................................14%
dry mouth...........3%.................................4%...........................................9%
somnolence.........1%.................................4%...........................................9%
dizziness..............2%.................................4%...........................................7%
sweating increased1%.................................3%...........................................8%
constipation.........1%.................................3%...........................................6%
fatigue.................2%.................................2%...........................................6%
indigestion...........1%.................................2%...........................................6%

The overall incidence rates of adverse events in 10mg Lexapro treated patients (66%) is similar to that of the placebo treated patients (61%), while the incidence rate in 20mg Lexapro treated patients was greater (86%).


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