Posted by Shawn. T. on July 13, 2002, at 2:49:21
In reply to Re: Let me help you; a must read, posted by cybercafe on July 12, 2002, at 23:47:56
Ritanserin does not bind to 5-HT2C receptors.
See
http://www.gpcr.org/7tm/ligand/Organon/Tablig/LIG_C87051432.htmlThat would be predictive of lack of efficacy in schizophrenic patients.
http://www.biopsychiatry.com/ritanserin.htm
Interestingly enough, I never bothered to see if clinical trials on mirtazapine (Remeron) had been conducted on schizophrenic patients. See
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=16273394Nice to see confirmation of my theories regarding schizophrenia. This would seem to effectively negate claims that schizophrenia can be treated with dopaminergic agents. Drugs which modulate dopamine release are the key to treating schizophrenia.
Also on the effectiveness of Ritanserin, it has been shown to be about as effective as SSRI's. You may recall that mirtazapine has been shown to be more efficacious in depression treatment than SSRI's. See
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=29479403I wonder why there is no mention in the Cochrane report of Remeron.
I really appreciate your comments cybercafe. I'm glad to hear you are doing so well.
poster:Shawn. T.
thread:112135
URL: http://www.dr-bob.org/babble/20020709/msgs/112193.html