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Re: Buspar and antibiotics? » Flopka

Posted by jay on April 27, 2002, at 15:42:25

In reply to Buspar and antibiotics?, posted by Flopka on April 26, 2002, at 23:52:06


I'd say stick with the Buspar, and see how it goes. You may want to wait until you get your body clear of the antibiotics, then get a few weeks "baseline" of just Buspar again. It is such a complicated relationship between meds, I don't think it is quite fair to say you would be getting 13x or so the "benefit", if you know what I mean.

Buspar seems to be working, so just stick with it, period. Blood levels are not always indicative of theraputic levels either, and if you start, stop, and restart, that can mess things up even more. Hang in there, keep it in your mind you are feeling well besides the "chemistry", and I'd imagine you have found the med that works excellent for you.

Best wishes..

Jay


> I know that Buspar supposedly has some issues with erithromycin interaction (it raises the level of buspirone something like 5 to 13 times?). But is this also true of other antibiotics? My doctor prescribed me Sulfameth for a sinus infection and I started taking both prescriptions a couple weeks ago. You might recall I reported almost instant results with the Buspar, despite starting on a low dose (10 mg). (Along with near total insomnia...)
>
> Well, I stopped taking the Sulfameth, and around the same time, the Buspar "stopped working." I didn't think anything of it at the time, I was kind of disappointed because the Buspar wasn't helping any longer, and wondering if it was just a big placebo effect or some kind of startup effect. But this evening I took Sulfameth again, and bingo. The calm feeling, the insomnia, exactly the way I felt when I first started on the Buspar. (I am on 15 mg of Buspar now)
>
> My question is, if Sulfameth has a heightening effect on levels of Buspar, is this safe that I've been (possibly) at these wildly fluctuating doses? What should I do now - quit the Buspar and start the titrating regimen over again, or just "enjoy it"? (well I can't really, the calm feeling is a wonderful relief, but the sleeplessness probably isn't very healthy)


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