Re: Relationship btw 1/2 life and onset of action?

Posted by Elizabeth on April 5, 2002, at 8:42:37

In reply to Relationship btw 1/2 life and onset of action?, posted by Janelle on April 5, 2002, at 2:04:32

AFAIk, you can't predict the time to onset of a drug's action based on its elimination half-life. The time it takes for a drug to start working has to do with things like how fast it's absorbed and taken up into the CNS, not with the rate of elimination.
HTH
-elizabeth

Thread

Could someone explain HALF-LIFE w/ example! Janelle 4/4/02
Half-Life: Explained with Examples and Importance » Janelle fachad 4/4/02
FACHAD:Thanks, great stuff, one teeny question: » fachad Janelle 4/4/02
Re: Could someone explain HALF-LIFE w/ example! » Janelle Sunnely 4/4/02
Sunnely: wow, thanks, how do you know this stuff?! (nm) » Sunnely Janelle 4/4/02
FACHAD: I still need YOUR answer to quest above! (nm) Janelle 4/4/02
Re: FACHAD:Thanks, great stuff, one teeny question: » Janelle fachad 4/4/02
RELATIONSHIP BTW 1/2 LIFE AND ONSET OF ACTION? Janelle 4/4/02
FACHAD: 2 questions 4 U (1/2 lives revisited!) Janelle 4/4/02
Relationship btw 1/2 life and onset of action? Janelle 4/5/02
SUNNELLY: could you answer this one also please?! (nm) Janelle 4/5/02
Re: Relationship btw 1/2 life and onset of action? Elizabeth 4/5/02
elimination half-life stuff Elizabeth 4/5/02
How Many Half-Lives Until it's Gone? » Janelle fachad 4/5/02
Re: Relationship btw 1/2 life and onset of action? » Janelle IsoM 4/5/02
ELIZabeth: what does ^- mean? (nm) » Elizabeth Janelle 4/5/02
How can 1/2 life be SAME for DIFF concentrations? Janelle 4/5/02
FACHAD: what does GC/MS stand for? (nm) » fachad Janelle 4/5/02
ELIZABETH: what do AFAIk and HTH stand for?! (nm) » Elizabeth Janelle 4/5/02
FACHAD: you forgot my second question, here it is: » fachad Janelle 4/5/02
What does ^- mean in a computation? Janelle 4/5/02
Re: What does ^- mean in a computation? » Janelle JohnX2 4/5/02
What ^(-5) means » Janelle IsoM 4/5/02
AFAIk/as far as I'm concerned HTH/hope that helps (nm) » Janelle IsoM 4/5/02
...
Re: Adam, I have no idea what you did! what is ''e''? 2sense 4/15/02

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poster:Elizabeth thread:101843
URL: http://www.dr-bob.org/babble/20020402/msgs/101957.html