Posted by Ritch on February 13, 2002, at 12:51:52
In reply to dopamine and norepinephrine question, posted by Michael D on February 13, 2002, at 11:10:07
> Is it possible that the reason why SSRI's seem to work for the first few days after I have an increase in dose, is due to the seratonin, dopamine and norepinephrine reacting at different rates?
>
> Michael DI suppose so in some round about way. Or it could simply be that everytime you increase the dose of SSRI your body has to "readjust" yet again. Perhaps the process of "readjustment" to a stimulus (dose increase) is the actual antidepressant mechanism (perhaps the "changing rates" you spoke of). That is kind of scary, though. It might explain SSRI "poop-out". That might also explain why continually switching antidepressants may work for some people to maintain antidepressant response. Obviously those processes need to be looked into closer (they probably are).
Mitch
poster:Ritch
thread:93981
URL: http://www.dr-bob.org/babble/20020208/msgs/93987.html