Posted by Peter Jay on February 4, 2002, at 16:17:19
In reply to Re: How do I safely augment SSRIs with anafranil?, posted by bob on February 4, 2002, at 16:07:06
She took many months to get to where she is now because the half-life of Prozac is so long (maybe a week or so), so each dose increment was slow.
She started very caustiously (after a former bad response to 20mg Paxil which she discontinued) and it went like this:
5mg to 15mg over 3 weeks
20mg to 60mg over 8 weeks
70mg to 100mg over 6 weeks
at 100mg since mid-November (approx 11 weeks).I think she has given the prozac long enough to show therapeutic benefit. It has produced some benefit but nothing like as much as the 175mg of anafranil was doing.
I am thinking that as she is free of all adverse side effects then she may be metabolising the prozac in such a way that it does not produce sufficiently high serotonin levels in her. After all, at 100mg she should be displaying some signs (side effects) of high serotonin.
Can you suggest an approach for augmentation?
Thanks!
Peter
poster:Peter Jay
thread:92851
URL: http://www.dr-bob.org/babble/20020131/msgs/92854.html