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Richelson: Memantine for Adderall tolerance

Posted by AndrewB on April 15, 2001, at 23:32:57

I have dysthymia and avoidant personality. I take Adderall for motivation, mental vigilence , arousal and improved confidence. Adderall alone though wears off after 3 days and I'm only left irritable and tired. I would take 2 day 'holidays' from adderall to restore its effect.

Now I take memantine, a partial NMDA antagonist. With it, adderall has a continuous effect. I have no irritability or poop out. I know memantine has been shown to prevent tolerance to certain drugs (i.e. cocaine and opiates). Can you explain to me how memantine prevents adderall tolerance. Also are there any safety issues when using such a medicine. (BTW, my doctor prescribes it from Germany since it is still undergoing trials in the US.)

Thank you,

AndrewB

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poster:AndrewB thread:60008
URL: http://www.dr-bob.org/babble/20010411/msgs/60008.html