Posted by blackjack on February 28, 2001, at 20:48:03
In reply to Wellbutrin -- anhedonia (long), posted by blackjack on February 27, 2001, at 21:50:35
I've been doing some reading, and here's what I think: my dopamine levels are shot. Dopamine plays a big role in pleasure. Parnate, the most effective med I've taken so far, is probably the most dopaminergic antidepressant availible. Tho Wellbutrin seems to block DA reuptake somewhat, it's not much except at high doses, and it may even suppress DA release. I'd bet that, knowing full well that drugs never work on me quite right, that Wellbutrin has either lowered my NA levels, or at least failed to boost them as effectively as the Parnate. The Wellbutrin does seem to have gotten my norepinephrine levels in order, thus accounting for my increased get-up-and-go...
So, the question is, what can I add to the Wellbutrin to give my dopamine levels a boost? Serzone's DA agonism is questionable. I know there are a lot of Parkinson's drugs out there, but I have no point of reference for them.
Thanks again.
poster:blackjack
thread:55049
URL: http://www.dr-bob.org/babble/20010221/msgs/55170.html