Posted by natg on February 10, 2001, at 0:07:52
In reply to Mirapex is a gift from God!, posted by SalArmy4me on February 9, 2001, at 19:20:29
Hi,
I, too, have been taking mirapex for several months now and it has been the best thing that's happened to me.
you are very lucky that you have no side- effects from it. I take 3.5 a day and at this dose I feel very nauseated.
do you take mirapex with food? have you experienced any weight gain? do you take any other meds?Thanks for your post. I'm thrilled that mirapex is working for you.
All the best,
Nat
######
> Mirapex is a dopamine agonist that is most often used for Parkinson's Disease. But, it has been shown in two studies to have antidepressant properties in non-Parkinson's patients.
> First, the background: I have treatment-resistant depression with painful flashbacks and Obsessive-Compulsive Disorder.
> It started working for me in a little less than a week (possibly because I got up to 6 mg per day in two days' time)! I found out that it needs to be taken about every 5 hours, otherwise I relapse. I have no side-effects from it (thank God).
> Studies on Medline:
> 2. Pramipexole augmentation in the treatment of unipolar and bipolar depression: a retrospective chart review Ann Clin Psychiatry. 2000 Sep;12(3):137-40. [Record as supplied by publisher] PMID: 10984002
> 3:
> Maj J, Rogoz Z.
> Related Articles
> Synergistic effect of pramipexole and sertraline in the forced swimming test. Pol J Pharmacol. 1999 Nov-Dec;51(6):471-5.
> PMID: 10817524
> 4: Corrigan MH, Denahan AQ, Wright CE, Ragual RJ, Evans DL. Related Articles Comparison of pramipexole, fluoxetine, and placebo in patients with major depression. Depress Anxiety. 2000;11(2):58-65. PMID: 10812530
> 5: DeBattista C, Solvason HB, Breen JA, Schatzberg AF. Related Articles Pramipexole augmentation of a selective serotonin reuptake inhibitor in the treatment of depression. J Clin Psychopharmacol. 2000 Apr;20(2):274-5. No abstract available. PMID: 10770475
> 6:
> Goldberg JF, Frye MA, Dunn RT.
> Related Articles
> Pramipexole in refractory bipolar depression.
> Am J Psychiatry. 1999 May;156(5):798. No abstract available.
> PMID: 10327923
> 7:
> Bennett JP, Piercey MF.
> Related Articles
> Pramipexole--a new dopamine agonist for the treatment of Parkinson's disease. J Neurol Sci. 1999 Feb 1;163(1):25-31. Review.
> PMID: 10223406
> 8: Piercey MF. Related Articles Pharmacology of pramipexole, a dopamine D3-preferring agonist useful in treating Parkinson's disease. Clin Neuropharmacol. 1998 May-Jun;21(3):141-51. Review. PMID: 9617505
> 9:
> Willner P.
> Related Articles
> The mesolimbic dopamine system as a target for rapid antidepressant action. Int Clin Psychopharmacol. 1997 Jul;12 Suppl 3:S7-14. Review.
> PMID: 9347387
poster:natg
thread:53626
URL: http://www.dr-bob.org/babble/20010131/msgs/53645.html