Posted by JackD on December 5, 2000, at 21:52:00
In reply to Any other drugs or combos like Wellbutrin?, posted by Lynne on December 3, 2000, at 9:41:11
Wellbutrin's mechanism in the brain is very poorly understood. I'm sorry, but I don't think there are any drugs that mimic it's effects.
Although Wellbutrin does cause the reuptake of Norepinephrine, Seratonin, and Dopamine (listed in order of reuptake, from highest to lowest), it does so only at doses much higher than the 300mg/day recommended therapeutic dosage.
There's much more to Wellbutrin's metabolism in the body than meets the eye. If you go to rxlist.com, you can read a little about it.
I myself have responded incredibly well to Wellbutrin, and no combination of Reboxetine/Stimulant, Remeron/Stimulant, or other combination felt quite the same, although some did work in helping the depression.
Ok, what I'm trying to say is I'm sure another combo will help, maybe even as much as the Wellbutrin, but I don't think any other will feel the same.
poster:JackD
thread:49841
URL: http://www.dr-bob.org/babble/20001130/msgs/50007.html