Posted by JackD on November 17, 2000, at 0:12:41
Sigh... here I am again, back to where I started. I sincerely empathize with all of you who have had unsuccesful drug trials. Hopefully, one of you can help me figure out the root of my problem...
Here's my story:
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I started out with ADD and dysthemia(but I thought I was just lazy). Took Ritalin 5mg 3x a day. AMAZING results: increased concentration, motivation, work capacity.BUT, my previous obsessiveness and anxiety were further excacerbated by the ritalin. I wanted to be un-ADDish and unanxious.
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So, I tried Paxil 20mg for 3 weeks. Nothing.---------------------
Then, I tried Wellbutrin SR 150 mg 1x a day. Amazing at first. No inhibitions, no anxiety, social confidence and performance increased tremendously. Made me feel always "in the moment" rather than disconnected.
BUT, the Wellbutrin helped less and less as the weeks went by. Eventually, it began making me morbidly depressed. More depressed than I've ever been in fact.
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So, I've stopped the Wellbutrin. I am trying different doses of Klonopin at the moment. It helps me physically, like keeps me from being fidgety in anxious situations, or sweating, and seems to keep me from panicking, but I feel a low level depression and mental anxiety.
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That's my story. There seems to be some dopamine-related chemistry problem. Could the Wellbutrin have been acting as a D2-D3 antagonist somehow? Is that what I might need? Amisulpride? I am so confused. Should I try another SSRI like Zoloft (it has Dopamine Re-Uptake properties). Is there any way to make the Wellbutrin work again? Lithium augmentation?
P.S. The Wellbutrin made me somewhat psychotic at times. It was really unpredictable. But when it worked, God, it worked.P.P.S. I have sleep problems. Never went to a doctor for it, but I always have nightmares and sleep WAY too much.
poster:JackD
thread:48949
URL: http://www.dr-bob.org/babble/20001115/msgs/48949.html