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Re: olanzapine, trichotillomania side effects » rapunzel

Posted by SLS on August 3, 2000, at 10:48:46

In reply to olanzapine, trichotillomania side effects, posted by rapunzel on August 2, 2000, at 0:48:41

> Does anyone out there know anything about Olanzapine? I just completed a study in which this med was given to treat trichotillomania (compulsive hair pulling). I was fine during the drug trial, and I did have significantly less pulling urges, but now that the trial is over I have been plunged into a terrible depression.
>
> This whole experience has really thrown me for a loop. If I had had ANY idea that I was giving up my peace of mind for hair... Any anecdotal info on this drug will be most apprectated!
>
> Rapunzel


Dear Rapunzel,

You have a good sense of humor. :-)

I can’t offer any personal accounts of this phenomenon with olanzapine (Zyprexa). However, I can attest to the capacity of another antipsychotic (sulpiride) to produce such a syndrome. I believe that the discontinuation of Zyprexa could account for the emergence of your depression. It probably unmasked your vulnerability to depression or a depressive counterpart of your illness. I would guess that this depression would abate by the end of the third week after discontinuation. This phenomenon is considered a rebound depression, and is not unheard of. I think the choice of Celexa as an antidepressant makes sense, as Zyprexa, like Celexa, possesses serotonergic properties.

I hope Celexa works out for you. Is your doctor using it as an OCD drug?


- Scott

 

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