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Re: adrafinil

Posted by michael on June 21, 2000, at 13:17:52

In reply to adrafinil, posted by elise on June 20, 2000, at 21:15:09

>
> What exactly is adrafinil? Why can you order it without a prescription?
> elise
\

Adrafinil was a med developed in France. The second generation of that med is called modafinil - known in the us by the brand name Provigil.

It, like provigil, is thought to work via stimulation of the alpha-1 receptors - which are the receptors norepinephrine stimulates.

However, they're not exactly sure of the precise mechanism or method of action for either (I believe all of the above is accurate - someon please correct me if I'm mistaken, or add if I've left stuff out)

You can't get it in the states because unlike provigil, adrafinil has not been FDA apporved. In my opinon, most likly because there is no profit incentive. It's relatively cheap, so unlikely to generate $'s to cover lengthy trials, and no $'s for profit thereafter. (Provigil, on the other hand, is very expensive - lots of profit margin)

You can order it from abraod. Some pharmacies may require a prescription, some do not (eg nubrain). You can import up to a three month supply per order, for personal use - FDA rules.
michael


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URL: http://www.dr-bob.org/babble/20000619/msgs/38001.html