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Re: SLS - Protocol for Unstable Chemistry

Posted by SLS on May 6, 2000, at 9:01:43

In reply to Re: SLS - Protocol for Unstable Chemistry, posted by JohnL on May 6, 2000, at 4:41:22

Thanks John. I appreciate your taking the time to answer my plea for help. I am feeling worse, becoming more vegetative, and losing my ability to read and think. No more intellectual stuff for a while, I guess.

Much of what you have described seems to ring true with me.

Your comment regarding lithium has got me thinking about trying it again. I hate that damned drug. Even at 600mg/day, I feel washed-out, flat, and passified. Unfortunately, I guess it might be the only drug to fill the role. I really should have given it a short trial the last time I was taking Parnate + a tricyclic. Lithium is supposed to be a good augmenter of Parnate.

I am considering performing a brief trial of adding Neurontin to the Lamictal 300mg I am currently taking. I would like to stay with low dosages, hopefully between 900-1200mg. The first time I tried it, higher dosages produced intolerable cognitive effects. I would not spend any more than two weeks with this. Some of the newer anticonvulsants have been suggested for me to take a look at, namely tiagabine (Gabitril).

I am having a difficult time deciding on whether to return to Parnate immediately or try some other things first. One of the big questions I am working with is what I will be able to add to Parnate. Have you ever heard of either amisulpride or adrafinil/modafinil being combined with Parnate? I think it makes sense to try other things first, as to start with Parnate and add things to it represents a committment of a huge amount of time.

I do like the idea of using short trials with stimulants, neuroleptics, lithium, and anticonvulsants when treating depression, particularly when they are being added to an antidepressant. To create the sort of structure you are suggesting makes a great deal of sense to me, and I will try to employ it.

Please, if you can think of anything else, I would be most grateful if you would post or contact me via e-mail.

Thanks.

sl.schofield@worldnet.att.net


- Scott

 

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