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Prozac vs. Serzone--some random comments

Posted by jd on February 10, 2000, at 19:25:44

In reply to Re: Scott, Cam, Cindy, posted by Scott L. Schofield on February 10, 2000, at 7:33:06


It's hard to say exactly why one med works
and another doesn't. This being said, I'll
add a few things to the above thread:

-- I've tried a lot of ADs, including Serzone.
For me, Serzone had nothing resembling the
effects I typically associate with NE-boosting
meds (such as tricyclics, effexor,
or mianserin). On the contrary, it did feel
rather serotenergic. This is subjective data
of course, but not entirely meaningless.

--Many people on this board have hypothesized
that bad reactions to Serzone might have
something to do with one of its metabolites,
MCPP. Especially when MCPP breakdown is
blocked by coadministration of another med,
this could explain the paradoxical anxiety
and hostility some people feel while taking
it. Personally, I've yet to hear
of or read an anecdote about someone who's had
*great* response to Serzone, though I guess
such people are out there somewhere.

--jd

> > In summary though I believe pretty strongly that how any drug works, or doesn't work, for a particular person is determined by many different factors at a molecular level involving the unique chemistry of that person. So to me the fact that literature seems to be in confusion of Serzone NE reuptake, it is nearly irrelevant as I see it. All that matters is that during a personal trial it either works or doesn't work. I wish I could understand all the whys and hows. I don't think I ever will. I'd be happy just to get well. JohnL
>
> Bull's-eye.
>
> > I'd be happy just to get well.
>
> I just wanted to see this written one more time.
>
> I would gladly give up all my psychopharm knowledge (of questionable quality and value) for mental health.
>
>
> - Scott
>
>
> An enthusiastic teen-age daughter of a New York Yankees VIP was given the opportunity to visit the team locker-room before a game. Being a big fan of Yogi Berra, she walked up to him and said, "Mr. Berra, I think you're the coolest." To that, Yogi replied, "Thank-you. You're not so hot yourself."


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poster:jd thread:20849
URL: http://www.dr-bob.org/babble/20000209/msgs/21050.html