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DHEA, 7-KETO™, my experience so far

Posted by Diane on February 8, 2000, at 16:12:55

In reply to DHEA, posted by Reenee N on February 5, 2000, at 1:04:08

I posted some of this a month or so ago. This is an updated version.

I am a 45yr old female, perimenopause.
I started taking 25mg DHEA 12/14/99 Within the first week my hair stopped falling out! and my skin is clearing (drying) up!

Background:
At age of 35 my face, for the first time in my life, started to break out... in acne! and over the next 6 yrs into cysts. I finally got it under control with antibiotics but have
always had to wash with Clearasil soap (smells just like pet soap) and apply a 10% Benzoyl Peroxide gel. At around age 38 my hair started falling out. At first allot then just slowly...up until
DHEA. Oh, I also around this same time frame (age 38) started having facial hair, about 20 dark hairs on either side of my chin (gross!)...well that is subsiding alittle as well. I don't have to shave as often.
That's right shave :o( Bleach doesn't cut it and hair removers hurt my skin. Electrolysis, I never looked into.

This is the first time I have ever taken a supplement that has actually had a notable effect. I have experienced no ill effects so far EXCEPT weight gain, which I am not sure is due to the DHEA or the fact that I have stopped walking my 5miles a day due
to the weather. According to all I've read (side effects include acne, irritability, fatigue, accelerated growth of facial hair and hirsutism in women) my experience has been just the opposite. My next complete physical is in 7 months...we'll see how it really goes
then.

EMOTIONALLY I'm not as negative, am alittle more steady. I feel more alive/awake. I smile and laugh more, I kid you not! It hasn't had any negative emotional effects ...so that's positive.
Just brushing my hair and having only 3 hairs in the brush (instead of 50) and 3 on the floor is enough to lift my mood.
I still use the Clearasil soap but very sparingly. Same with the Benzoyl Peroxide gel and Retin-A...very sparingly.

WHAT'S NEW. 2 weeks ago I ran into 7-oxo DHEA (7-KETO™), a naturally occurring metabolite of DHEA, at these web sites:

http://whyfiles.news.wisc.edu:80/103fat2/4.html
http://www.7keto.com/abstract.html
http://www.7keto.com/index.html


....7-oxo DHEA (7-KETO™):

"Unlike DHEA, which is the most common hormone in the blood of a young adult, 7-oxo DHEA (7-KETO™) is not found in the blood of adults, although it is produced in the kidneys.

And while DHEA raised blood levels of testosterone in women as much as 10 times above normal, 7-oxo DHEA does *NOT* significantly affect levels of sex hormones.

The compound has passed toxicity tests, which looked at enzymes in the liver and blood hormone levels, and shown itself to be "completely innocuous,". Lardy, chairman emeritus of the Enzyme Institute at the University of Wisconsin-Madison, says "No-one has found any adverse side effects."

What does 7-oxo do?
There are *signs* that it mimics *thyroid* hormone, which causes the body to make more heat, thus burning more calories without really doing anything. An early clinical trial published in the Journal of Exercise Physiology Online looked at 30 obese people who took either a placebo or 7-KETO™, a
commercial version of 7-oxo that's sold as a food supplement.

Both groups took three one-hour sessions of aerobic and anaerobic exercise per week. At the end of the eight-week study, the 7-KETO™ group had lost 1.8 percent of body fat, compared to 0.57 percent among the placebo exercisers. Their overall weight loss was 2.88 kilos, about three times the loss
among those who took the placebo.

That's a preliminary study, and hardly reason to jump out and buy the stuff.

If 7-oxo is promising, Lardy indicates that even better compounds are lurking in the wings. "We found [7-oxo] on the pathway to the active hormone, but it's not the active hormone." While 7-oxo is more powerful than DHEA, the active hormone might be yet more potent -- if and when it's isolated.
Indeed, we should be speaking in the plural here. "DHEA has so many effects," Lardy says, "that it's not likely that a single hormone would have all those effects." "
-------
I went out the next day and bought some 7-KETO™. The only effect I immediately noticed was a diuretic effect, especially when taken on an empty stomach. That's about it so far.
-------
I have no idea of AD, DHEA interaction. DHEA is a hormonal thing. The only warnings I've seen are "Not to be used by those under 18yrs., pregnant/lactating women, those with liver disorders, men with prostate cancer and women with reproductive cancers and /or reproductive pre-cancerous conditions, breast cancers or
related conditions."
-------
Book recommendation. I've mentioned this book twice before but here it is again.
SCREAMING TO BE HEARD, Hormonal Connections Women Suspect...and
Doctors Ignore by Elizabeth Lee Vliet, M.D.
See it at Amazon.com
http://www.amazon.com/exec/obidos/ASIN/0871317842/o/qid=947127544/sr=2-1/102-2670982-7224813
-------
http://www.smartbasics.com/glossary/dhea_glos.htm
http://www.webadprod.com/dhea/dheafaq.htm

Misc. tip: :o)
Cutting out all CAFFEINE has been a real life saver for me. Caffeine makes me angry, then frustrated, than depressed...boom boom boom ...in that order.
-------end, finally eh?


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poster:Diane thread:20549
URL: http://www.dr-bob.org/babble/20000128/msgs/20785.html