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Re: switching from moclobemide to Parnate

Posted by Joanna on October 23, 1999, at 2:11:02

In reply to Re: switching from moclobemide to Parnate, posted by JohnL on August 14, 1999, at 10:34:37

> Joanna, I tried Moclobemide once. Bad reaction on first dose, so abondoned quickly. But I had done lots of research on it. One reason I chose it was because of the short washout period if anything went wrong. SSRIs can be started just two days after stopping Moclobemide. I'm not sure about Parnate, but to be safe I would wait a week and then approach Parnate cautiously with as low a dose as possible, maybe every other day instead of daily for a few days, just to feel it out and be safe. Hopefully someone else here can help more, but as I understand it, Moclobemide's washout period is very short. As a sidenote, the Canadian doctor I saw was real good, and he said he augments Moclobemide with low doses of about every AD out there (except other MAOIs). Hope it all goes well for you. JohnL.

Thank You John for replying. So far I've tried to augment Moclobemide with Dexedrine, and Ritalin. I just have lost response to maximum dozes. Moreover, Dexedrine+Moclobemide combo gave me bad interaction later on -chest pain, heart problems. I've tried to augment Moclobemide with Naltrexone, and it worked. It looks like Naltrexone was the first drug that broke the nonresponse in me. I've read Your postings, and will be interested to e-mail You.

Joanna.


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