Psycho-Babble Neurotransmitters Thread 969434

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How to inhibit MKP-1

Posted by Tomatheus on November 9, 2010, at 16:36:45

It has come to my attention that there is evidence for the expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) being elevated in the brains of depressed patients:

http://behavioralhealthcentral.com/index.php/20101018239833/Pharma-News/phosphatase-may-be-target-for-novel-antidepressant-approach.html

http://www.nature.com/nm/journal/v16/n11/full/nm.2219.html

Does anyone know of a way to inhibit the MKP-1 protein or to otherwise reduce its expression?

Tomatheus


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